A paediatric case of successful non‐myeloablative bone marrow transplantation after azacitidine therapy for non‐Down syndrome acute megakaryoblastic leukaemia with monosomy 7 | Zendy

Koga Yuhki | Zendy; Oba Utako | Zendy; Kato Wakako | Zendy; Ono Hiroaki | Zendy; Nakashima Kentaro | Zendy; Takada Hidetoshi | Zendy

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A paediatric case of successful non‐myeloablative bone marrow transplantation after azacitidine therapy for non‐Down syndrome acute megakaryoblastic leukaemia with monosomy 7

Author(s) -

Koga Yuhki,

Oba Utako,

Kato Wakako,

Ono Hiroaki,

Nakashima Kentaro,

Takada Hidetoshi

Publication year - 2016

Publication title -

pediatric transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.457

H-Index - 69

eISSN - 1399-3046

pISSN - 1397-3142

DOI - 10.1111/petr.12739

Subject(s) - medicine , azacitidine , acute megakaryoblastic leukemia , monosomy , transplantation , chemotherapy , regimen , chemotherapy regimen , down syndrome , oncology , leukemia , pediatrics , karyotype , psychiatry , biochemistry , gene expression , chemistry , dna methylation , chromosome , gene

We report a patient with non‐Down syndrome AML , also known as AMKL, with monosomy 7, who was also obese and had a hearing impairment and mental retardation. Non‐myeloablative bone marrow transplantation was performed successfully after the patient received less aggressive azacitidine treatment, without the usual intensive induction chemotherapy regimen for AML .

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