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Review of combined liver and kidney transplantation in children
Author(s) -
Ganschow Rainer,
Hoppe Bernd
Publication year - 2015
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.12593
Subject(s) - medicine , transplantation , liver transplantation , kidney transplantation , kidney , surgery
In this review, we focused on CLKT with regard to indication, results, outcome, and future developments. PH 1 is one of the most common diagnoses for adult and pediatric patients qualifying for CLKT . The other major indication for combined transplantation is ARPKD . CLKT appears to be superior to sequential liver and kidney transplantation in the majority of patients and overall results following CLKT are now good, even in small children. Clinical observations suggest that there is an immunological advantage of CLKT in comparison with isolated liver or kidney transplantation. More clinical studies are necessary to identify the best candidates for CLKT while the availability of donor organs is low.