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Lifesaving liver transplantation for multi‐organ failure caused by B acillus cereus food poisoning
Author(s) -
Tschiedel Eva,
Rath PeterMichael,
Steinmann Jörg,
Becker Heinz,
Dietrich Rudolf,
Paul Andreas,
FelderhoffMüser Ursula,
DohnaSchwake Christian
Publication year - 2015
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.12378
Subject(s) - medicine , bacillus cereus , rhabdomyolysis , enterotoxin , food poisoning , microbiology and biotechnology , diarrhea , toxin , cereus , ingestion , context (archaeology) , liver transplantation , transplantation , gastroenterology , bacteria , biology , pathology , biochemistry , escherichia coli , paleontology , genetics , gene
Bacillus cereus is a spore‐forming, gram‐positive bacterium that causes food poisoning presenting with either emesis or diarrhea. Diarrhea is caused by proteinaceous enterotoxin complexes, mainly hemolysin BL, non‐hemolytic enterotoxin (NHE), and cytotoxin K. In contrast, emesis is caused by the ingestion of the depsipeptide toxin cereulide, which is produced in B. cereus contaminated food, particularly in pasta or rice. In general, the illness is mild and self‐limiting. However, due to cereulide intoxication, nine severe cases with rhabdomyolysis and/or liver failure, five of them lethal, are reported in literature. Here we report the first case of life‐threatening liver failure and severe rhabdomyolysis in this context that could not be survived without emergency hepatectomy and consecutive liver transplantation.