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Functional capacity after pediatric liver transplantation: A pilot study
Author(s) -
Maria da Silva Rosângela,
Brunow de Carvalho Werther,
Johnston Cíntia,
Borba de Castro Mariela,
Manta Ferreira Israel,
Patti Camilla L.,
Anthero de Azevedo Ramiro,
Miziara Gonzalez Adriano,
Moura Linhares Marcelo,
Augusto SalzedasNetto Alcides
Publication year - 2014
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.12318
Subject(s) - medicine , anthropometry , reproducibility , liver transplantation , transplantation , body mass index , analysis of variance , vital capacity , prospective cohort study , pearson product moment correlation coefficient , body weight , surgery , lung , lung function , diffusing capacity , statistics , mathematics
The prospective cross‐sectional study investigated the 6 MWT performance in pediatric group of liver transplant recipients (6–17 yr, median post‐transplantation time of 22 months) and compared to the normal values obtained in healthy children as well as evaluated the reproducibility of the 6 MWT . We analyzed the relationship between walked distance and the 6 MW w, distance walked × body weight) with the anthropometric, clinical, and pulmonary functions. In post‐transplanted group, the average walked distance was significantly shorter compared with control (687 ± 80 m vs. 511 ± 72 m, p < 0.001). The calculated ICC coefficient confirmed the reproducibility among tests. The Pearson correlation revealed that only walked distance in the 6 MWT was moderately correlated with tidal volume. Conversely, the 6 MW w was significantly correlated with age, weight, height, BMI , FVC , PEF rate, and volume expiratory. According to multiple regression analysis, age, VE and FVC factors explained 80% of the variance in the 6 MW w. In conclusion, the pediatric liver transplant recipients' performance in the 6 MWT is significantly lower than the values for healthy children of the same age. Notably, the 6 MW w may provide relevant information, constituting an additional parameter in the determination of functional capacity.