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Factors predicting health‐related quality of life in pediatric liver transplant recipients in the functional outcomes group
Author(s) -
Alonso Estella M.,
Martz Karen,
Wang Deli,
Yi Michael S.,
Neighbors Katie,
Varni James W.,
Bucuvalas John C.
Publication year - 2013
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.12126
Subject(s) - medicine , logistic regression , quality of life (healthcare) , liver transplantation , demography , pediatrics , transplantation , nursing , sociology
Data from 997 pediatric LT recipients were used to model demographic and medical variables as predictors of lower levels of HRQOL . Data were collected through SPLIT FOG project. Patients were between 2 and 18 yr of age and survived LT by at least 12 months. Parents and children (age ≥ 8 yr) completed Peds QL ™ 4.0 Generic Core and CF Scales at one time point. Demographic and medical variables were obtained from SPLIT . HRQOL scores were categorized as “poor” based on lower 25% of scores for each measure. Logistic regression models were generated. Single‐parent households ( OR 1.94, CI 1.13–3.33, p = 0.017), anti‐seizure medications ( OR 3.99, CI 1.26–12.70, p = 0.019), and number of days hospitalized ( OR 1.03, CI 1.01–1.06, p = 0.0067) were associated with lower self‐reported HRQOL . Parent data identified increasing age at transplant, age 5–12 yr at survey, hospitalization >21 days at LT , re‐operations, diabetes, and growth failure at LT as additional predictors of generic HRQOL . Male gender, single‐parent households, higher bilirubin levels at LT , and use of anti‐seizure medication predicted lower cognitive function scores. HRQOL following pediatric LT is related to medical and demographic variables.