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Kidney grafts from donors ≤5 yr of age: Single kidney transplantation for pediatric recipients or en bloc transplantation for adults?
Author(s) -
Gallinat Anja,
Sotiropoulos Georgios C.,
Witzke Oliver,
Treckmann Jürgen W.,
Molmenti Ernesto P.,
Paul Andreas,
Vester Udo
Publication year - 2013
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.12049
Subject(s) - medicine , transplantation , young adult , kidney transplantation , renal transplant , kidney , single center , surgery , pediatrics , urology
Kidneys from donors ≤5 yr of age represent a controversial issue. The purpose of this study was to compare the transplant outcomes as single and single/en bloc grafts into pediatric and adult KT recipients, respectively. All recipients of kidneys from donors ≤5 yr old transplanted at our institution from 3/2003 to 12/2010 were evaluated, and corresponding data were analyzed. There were 11 pediatric and 14 adult recipients. Median donor age and body weight were 38 months and 14 kg, respectively. PNF , n = 2 and DGF , n = 1 were observed only among adult recipients. Five‐yr graft survival was 100% for children and 86% for adults. There were no significant differences in graft and patient survival, PNF , DGF , acute rejection, or postoperative complications among children/single (n = 10), adults/en bloc (n = 10), and adults/single (n = 4) KT . Major complications were documented in six adult recipients and one pediatric recipient after en bloc KT . Pediatric recipients showed significantly higher GFR during the first post‐transplant year. Kidneys from donors ≤5 yr of age have at least as good outcomes as when transplanted as single allografts into children. Although the study‐volume is small, it seems that children benefit from a pediatric‐oriented allocation policy.