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Long‐term outcomes of living donor kidney transplants in pediatric recipients following laparoscopic vs. open donor nephrectomy
Author(s) -
Chaykovska Lyubov,
Deger Serdar,
Roigas Jan,
Lenz Andre,
Lioudmer Poline,
Kothmann Lisa T.,
Friedersdorff Frank,
Müller Dominik,
Kasper Antje,
Giessing Markus,
Magheli Ahmed,
Kempkensteffen Carsten,
Lingnau Anja,
Fuller T. Florian
Publication year - 2012
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.12008
Subject(s) - medicine , nephrectomy , surgery , creatinine , kidney , renal function , retrospective cohort study , single center , urology , incidence (geometry) , kidney transplantation , transplantation , gastroenterology , optics , physics
We compared long‐term outcomes of LDKT in pediatric recipients following either laparoscopic ( LDN ) or ODN . In our retrospective single‐center study, we compared 38 pediatric LDKT recipients of a laparoscopically procured kidney with a historic ODN group comprising 17 pediatric recipients. In our center, the first pure laparoscopic non‐hand‐assisted LDN for a pediatric LDKT recipient was performed in June 2001. Demographic data of donors and recipients were comparable between groups. Mean follow‐up was 64 months in the LDN group and 137 months in the ODN group. Patient survival was comparable between groups. Graft survival at one and five yr was 97% ( LDN ) vs. 94% ( ODN ) and 91% ( LDN ) vs. 88% ( ODN ; p = n.s.), respectively. Serum creatinine at one and five yr was 1.16 ± 0.47 mg/dL ( LDN ) vs. 1.02 ± 0.38 mg/dL ( ODN ) and 1.38 ± 0.5 mg/dL ( LDN ) vs. 1.20 ± 0.41 mg/dL ( ODN ), respectively. The type and frequency of surgical complications did not differ between groups. DGF and acute rejection rates were similar between groups. In the ODN group, a higher proportion of right donor kidneys was used. In the ODN group, all kidneys had singular arteries, whereas in the LDN group five kidneys had multiple arteries. Arterial multiplicity was associated with a higher incidence of DGF . In our experience, LDN does not compromise long‐term graft outcomes in pediatric LDKT recipients. Arterial multiplicity of the donor kidney may be a risk factor for impaired early graft function in the pediatric population.

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