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Curative potential of allogeneic hematopoietic stem cell transplant in type 1 diabetes
Author(s) -
McCabe Kristen E.,
Pollock Allison J.,
Rehm Jennifer L.,
DeSantes Kenneth B.
Publication year - 2017
Publication title -
pediatric diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.678
H-Index - 75
eISSN - 1399-5448
pISSN - 1399-543X
DOI - 10.1111/pedi.12430
Subject(s) - medicine , type 1 diabetes , aplastic anemia , haematopoiesis , savior sibling , hematopoietic stem cell transplantation , stem cell , diabetes mellitus , hematopoietic stem cell , type 2 diabetes , insulin , hematopoietic cell , intensive care medicine , immunology , transplantation , endocrinology , bone marrow , biology , genetics
The mainstay of treatment for type 1 diabetes ( T1D ) is exogenous insulin. Here, we report a case in which exogenous insulin requirements were eliminated after an allogeneic hematopoietic stem cell transplant for aplastic anemia in a pediatric patient recently diagnosed with T1D , and explore the validity of this approach compared with current treatments.