Premium Clinical implementation of islet transplantation: A current assessmentPremium
Abstract Beta‐cell replacement is the only physiologically relevant alternative to insulin injections in patients with type 1 diabetes (T1D). Pancreas and islet transplantation from deceased organ donors can provide a new beta‐cell pool to produce insulin, help blood glucose management, and delay secondary diabetes complications. For children and adolescents with T1D, whole pancreas transplantation is not a viable option because of surgical complications, whereas islet transplantation, even if it is procedurally simpler, must still overcome the burden of immunosuppression to become a routine therapy for children in the future.
Subject(s)beta cell , diabetes mellitus , endocrinology , immunosuppression , insulin , intensive care medicine , islet , islet cell transplantation , kidney transplantation , medicine , pancreas , pancreas transplantation , surgery , transplantation , type 1 diabetes
SCImago Journal Rank1.678
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