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Demyelinating neuropathy in a 6‐year‐old girl with autism spectrum disorder
Author(s) -
Kamata Akiko,
Muramatsu Kazuhiro,
Sawaura Noriko,
Makioka Nishiki,
Ogata Tomomi,
Kuwashima Makoto,
Arakawa Hirokazu
Publication year - 2017
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/ped.13331
Subject(s) - medicine , magnetic resonance imaging , brachial plexus , demyelinating disorder , spectrum disorder , neuroimaging , autism spectrum disorder , weakness , pediatrics , surgery , radiology , autism , central nervous system , psychiatry
Herein we report the case of a 6‐year‐old girl with autism spectrum disorder ( ASD ) and weakness in the distal portion of the right upper limb. Although difficult to perform, nerve conduction studies indicated demyelinating neuropathy. Magnetic resonance imaging ( MRI ) showed swelling a nd high‐intensity signals in the right brachial plexus and cervical spinal roots. The symptoms recovered after a single course of i.v. immunoglobulin. Electrophysiological indices and MRI findings also improved after treatment. This case demonstrates the utility of neuroimaging in addition to electrophysiological assessments for the diagnosis of demyelinating neuropathy, particularly in young patients with ASD .