Haploidentical hematopoietic cell transplantation for disseminated  E wing sarcoma | Zendy

Yoshihara Hiroki | Zendy; Kumamoto Tadashi | Zendy; Ono Rintaro | Zendy; Akahane Keiko | Zendy; Nozaki Taiki | Zendy; Kobayashi Shogo | Zendy; Kikuta Atsushi | Zendy; Matsumoto Seiichi | Zendy; Hasegawa Daisuke | Zendy; Ogawa Chitose | Zendy; Manabe Atsushi | Zendy

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Haploidentical hematopoietic cell transplantation for disseminated E wing sarcoma

Author(s) -

Yoshihara Hiroki,

Kumamoto Tadashi,

Ono Rintaro,

Akahane Keiko,

Nozaki Taiki,

Kobayashi Shogo,

Kikuta Atsushi,

Matsumoto Seiichi,

Hasegawa Daisuke,

Ogawa Chitose,

Manabe Atsushi

Publication year - 2017

Publication title -

pediatrics international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.49

H-Index - 63

eISSN - 1442-200X

pISSN - 1328-8067

DOI - 10.1111/ped.13195

Subject(s) - medicine , sarcoma , prednisolone , transplantation , hematopoietic stem cell transplantation , hematopoietic cell , graft versus host disease , disease , surgery , oncology , immunology , haematopoiesis , pathology , stem cell , biology , genetics

We describe the case of a 13‐year‐old girl with multifocal disseminated Ewing sarcoma family of tumor ( ESFT ) who received a 5/8 human leukocyte antigen‐matched haploidentical hematopoietic cell transplantation to generate a graft‐versus‐tumor effect. The patient had grade 2 acute graft‐versus‐host disease ( GVHD ) of the skin and chronic GVHD nausea and abdominal pain that required prednisolone for 17 months, but has been free from ESFT for 3 years 10 months after therapy. The present case suggests a beneficial effect of haploidentical hematopoietic cell transplantation in disseminated ESFT .

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