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Haploidentical hematopoietic cell transplantation for disseminated E wing sarcoma
Author(s) -
Yoshihara Hiroki,
Kumamoto Tadashi,
Ono Rintaro,
Akahane Keiko,
Nozaki Taiki,
Kobayashi Shogo,
Kikuta Atsushi,
Matsumoto Seiichi,
Hasegawa Daisuke,
Ogawa Chitose,
Manabe Atsushi
Publication year - 2017
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/ped.13195
Subject(s) - medicine , sarcoma , prednisolone , transplantation , hematopoietic stem cell transplantation , hematopoietic cell , graft versus host disease , disease , surgery , oncology , immunology , haematopoiesis , pathology , stem cell , biology , genetics
We describe the case of a 13‐year‐old girl with multifocal disseminated Ewing sarcoma family of tumor ( ESFT ) who received a 5/8 human leukocyte antigen‐matched haploidentical hematopoietic cell transplantation to generate a graft‐versus‐tumor effect. The patient had grade 2 acute graft‐versus‐host disease ( GVHD ) of the skin and chronic GVHD nausea and abdominal pain that required prednisolone for 17 months, but has been free from ESFT for 3 years 10 months after therapy. The present case suggests a beneficial effect of haploidentical hematopoietic cell transplantation in disseminated ESFT .