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Evans syndrome after autologous peripheral blood stem cell transplantation for recurrent Hodgkin lymphoma
Author(s) -
Kato Ikuko,
Okada Hitoshi,
Nishida Tomoko,
Konishi Yukihiko,
Kondo Sonoko,
Nishisho Sae,
Iwase Takashi,
Itoh Susumu,
Kusaka Takashi
Publication year - 2016
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/ped.13030
Subject(s) - medicine , lymphoma , peripheral blood stem cells , stem cell , transplantation , autologous stem cell transplantation , hematopoietic stem cell transplantation , evans syndrome , refractory (planetary science) , haematopoiesis , non hodgkin's lymphoma , peripheral blood , hodgkin lymphoma , surgery , immunology , antibody , physics , autoimmune hemolytic anemia , biology , astrobiology , genetics
There have been a number of recent reports on the occurrence of autoimmune conditions after autologous hematopoietic stem cell transplantation. We describe a rare case of Evans syndrome ( ES ) that developed in a 16‐year‐old patient >1 year after autologous peripheral blood stem cell transplantation for recurrent Hodgkin lymphoma. ES is a rare and frequently refractory condition. No therapy for the condition has been established, and it can often be fatal. In the present case, i.v. cyclosporine A injection was significantly effective against the ES , which has not recurred.