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Repeated fecal microbiota transplantation in a child with ulcerative colitis
Author(s) -
Shimizu Hirotaka,
Arai Katsuhiro,
Abe Jun,
Nakabayashi Kazuhiko,
Yoshioka Takako,
Hosoi Kenji,
Kuroda Makoto
Publication year - 2016
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/ped.12967
Subject(s) - medicine , ulcerative colitis , fecal bacteriotherapy , feces , infliximab , colectomy , transplantation , gastroenterology , colitis , fecal incontinence , refractory (planetary science) , antibiotics , clostridium difficile , tumor necrosis factor alpha , disease , biology , paleontology , microbiology and biotechnology , physics , astrobiology
We report the case of an 11‐year‐old girl with ulcerative colitis refractory to conventional therapy, who was subsequently treated successfully with repeated fecal microbiota transplantation (FMT). The patient was steroid dependent despite several infliximab treatments, and colectomy was proposed to improve quality of life. After repeated FMT, she was able to maintain remission with on minimal dose of steroid. Although her fecal microbiota was dysbiotic before FMT, it was restored to a similar pattern as the donor after repeated FMT.