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Remitted epilepsy with dysembryoplastic neuroepithelial tumor involving the thalamus
Author(s) -
Nishikura Noriko,
Takano Tomoyuki,
Ryujin Fukiko,
Yoshioka Seiichiro,
Maruo Yoshihiro,
Takeuchi Yoshihiro,
Tamura Kentaro,
Sakakibara Takafumi,
Ito Masayuki
Publication year - 2016
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/ped.12911
Subject(s) - thalamus , medicine , epilepsy , lesion , electrocorticography , temporal lobe , intractable epilepsy , cortex (anatomy) , epilepsy surgery , pathology , neuroscience , radiology , psychology , psychiatry
Dysembryoplastic neuroepithelial tumors (DNT) are benign hamartomatous tumors characterized by intractable epilepsy and common localization in the supratentorial cortex, but thalamic involvement in DNT is extremely rare. A 2‐year 4‐month‐old boy presented with intractable epilepsy due to a tumorous lesion in the frontal lobe expanding to the thalamus. Under chronic intracranial electrocorticography guidance, partial lesionectomy with adjacent cortical resection was performed, and the lesion was pathologically diagnosed as DNT, complex form. Subsequently, the seizures completely disappeared without any neurological deficits despite the presence of full residual thalamic lesions. The epileptogenicity of DNT is closely associated with various clinicopathological factors, and the thalamic contribution to the seizure activity remains unclear. Due to the essential epileptogenic characteristics of DNT, the residual thalamic lesions and associated clinical features should be strictly observed in the future in the present case.