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Acute oral complications in a pediatric patient with acute lymphoid leukemia
Author(s) -
Kamasaki Yoko,
Satoh Kyoko,
Nishiguchi Miyuki,
Hoshino Tomonori,
Fujiwara Taku
Publication year - 2016
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/ped.12829
Subject(s) - medicine , pseudomonas aeruginosa , neutropenia , cellulitis , malignancy , acute leukemia , pneumonia , leukemia , pathogen , dermatology , immunology , chemotherapy , bacteria , genetics , biology
Pseudomonas aeruginosa is a low‐virulence pathogen that can cause infection in immunocompromised patients. Among pediatric hematologists, it is known that careful attention should be paid to P. aeruginosa as the bacteria responsible for intraoral inflammation, and antibiotic therapy targeting P. aeruginosa is the first‐line treatment during neutropenia in patients with hematological malignancy. Immunosuppressed patients, however, are at high risk of developing inflammation. Here, we report a case involving a 10‐year‐old patient with acute lymphoid leukemia (ALL), in which P. aeruginosa synergistically acted with pre‐existing gingivitis to induce unusual oral necrotic lesions, leading to acute buccal cellulitis and pus discharge from external sinus tracts.