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Successful diuretics treatment of protein‐losing enteropathy in N oonan syndrome
Author(s) -
Mizuochi Tatsuki,
Suda Kenji,
Seki Yoshitaka,
Yanagi Tadahiro,
Yoshimoto Hironaga,
Kudo Yoshiyuki,
Iemura Motofumi,
Tanikawa Ken,
Matsuishi Toyojiro
Publication year - 2015
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/ped.12603
Subject(s) - medicine , protein losing enteropathy , refractory (planetary science) , spironolactone , enteropathy , furosemide , diuretic , short bowel syndrome , gastroenterology , heart failure , cardiology , endocrinology , disease , parenteral nutrition , physics , astrobiology
There are few reports on successful high‐dose spironolactone treatment of refractory protein‐losing enteropathy ( PLE ) caused by Fontan procedure. We report successful diuretics treatment with spironolactone and furosemide at standard dose, of refractory PLE in a patient with N oonan syndrome and repaired congenital heart disease. This is the first successful application of diuretics treatment in a patient with refractory PLE without Fontan procedure. This case illustrates that diuretics treatment can be the first‐line treatment of PLE regardless of the causative physiology, and can be effective in refractory PLE with N oonan syndrome.