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Mumps encephalitis with akinesia and mutism
Author(s) -
Suga Kenichi,
Goji Aya,
Shono Miki,
Matsuura Sato,
Inoue Miki,
Toda Eiko,
Miyazaki Tatsushi,
Kawahito Masami,
Mori Kazuhiro
Publication year - 2015
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/ped.12581
Subject(s) - medicine , pediatrics , encephalitis , vaccination , measles , rubella , toddler , immunology , virus , psychology , developmental psychology
Measles‐rubella‐mumps vaccination is routine in many countries, but the mumps vaccine remains voluntary and is not covered by insurance in J apan. A 5‐year‐old J apanese boy who had not received the mumps vaccine was affected by mumps parotitis. Several days later, he presented with various neurological abnormalities, including akinesia, mutism, dysphagia, and uncontrolled respiratory disorder. Mumps encephalitis was diagnosed. Despite steroid pulse and immunoglobulin treatment, the disease progressed. Magnetic resonance imaging showed necrotic changes in bilateral basal ganglia, midbrain, and hypothalamus. At 1 year follow up, he was bedridden and required enteral feeding through a gastric fistula and tracheostomy. Mumps vaccination should be made routine as soon as possible in J apan, because mumps encephalitis carries the risk of severe sequelae.