Premium
Intraventricular hemorrhage as a comorbid factor for intestinal obstruction in very low‐birthweight infants
Author(s) -
Hisamatsu Chieko,
Morioka Ichiro,
Matsuo Kiyomi,
Iijima Kazumoto,
Nishijima Eiji
Publication year - 2015
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/ped.12548
Subject(s) - medicine , intraventricular hemorrhage , retinopathy of prematurity , incidence (geometry) , univariate analysis , gestational age , neonatal intensive care unit , mechanical ventilation , risk factor , bronchopulmonary dysplasia , pediatrics , multivariate analysis , pregnancy , genetics , physics , optics , biology
Abstract Background In very low‐birthweight infants ( VLBWI ), intestinal obstruction ( IO ) tends to increase in severity due to the immaturity of the intestine and perinatal events. We examined the clinical comorbid factors related to IO in VLBWI . Methods Clinical data of 160 VLBWI admitted to the neonatal intensive care unit in 2006–2011 were retrospectively reviewed. Patients were divided into two groups: IO group ( n = 62) and non‐ IO group ( n = 98). IO was defined as bile excretion via the mouth or nasogastric tube within 30 days after birth. The relationship between clinical factors and the incidence of IO was analyzed. Results On univariate analysis, gestational age, birthweight, and the incidence of chronic lung disease, patent ductus arteriosus, intraventricular hemorrhage ( IVH ), retinopathy of prematurity, and the postnatal use of mechanical ventilation, catecholamines, steroids, and sedatives were associated with IO . On multivariate analysis, only IVH was strongly associated with IO (OR, 4.74; P < 0.01). Conclusions IVH is a significant comorbid factor of IO in VLBWI .