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Nationwide survey of coronary aneurysms with diameter >6 mm in K awasaki disease in K orea
Author(s) -
Jang Gi Young,
Kang Iseok,
Choi Jae Young,
Bae Eun Jung,
Kim YoungHwue,
Kim Seong Ho,
Ma Jae Sook
Publication year - 2015
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/ped.12536
Subject(s) - medicine , aneurysm , aspirin , coronary artery disease , coronary stent , myocardial infarction , stent , artery , cardiology , coronary artery aneurysm , angioplasty , percutaneous coronary intervention , restenosis , stenosis , surgery , coronary angiography
Background We investigated the course of coronary aneurysm with diameter >6 mm in K awasaki disease ( KD ), as well as related therapeutic trends and prognosis in K orea. Methods A nationwide questionnaire survey was carried out in 77 hospitals, to investigate, retrospectively, patients with KD who had coronary aneurysms with a diameter >6 mm between 1990 and 2011. Results The median age of onset was 3 years (range, 2 months–16 years) in a total of 239 patients. During the acute stage of KD , most patients received i.v. immunoglobulins and aspirin. In addition, 27 patients received steroid therapy. In the current study, the mean coronary aneurysm size was 8.7 ± 3.2 mm (range, 6–21 mm). Twenty‐two patients underwent interventional catheterization. Procedures included percutaneous transluminal coronary balloon angioplasty ( n = 10), stent placement ( n = 9), and percutaneous transluminal coronary rotational ablation ( n = 3). Fourteen patients underwent coronary artery bypass graft surgery. Of the 239 patients who had coronary aneurysms with diameter >6 mm, 13 (5.4%) presented with findings suggestive of myocardial infarction. Five patients died during the follow‐up period. Conclusions Severe stenosis or occlusion of the coronary artery may occur in some patients who develop coronary aneurysms with diameter >6 mm; early management such as coronary interventions or surgery should be considered in such cases.