Premium
Hemophagocytic lymphohistiocytosis secondary to V aricella zoster infection in a child with H enoch– S chönlein purpura
Author(s) -
Gur Gokce,
Cakar Nilgun,
Uncu Nermin,
Ayar Ganime,
Basaran Ozge,
Taktak Aysel,
Koksoy Adem Yasin,
Acar Banu,
Caycı Fatma Semsa
Publication year - 2015
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/ped.12523
Subject(s) - medicine , hemophagocytic lymphohistiocytosis , cytopenia , coagulopathy , macrophage activation syndrome , immunology , malignancy , purpura (gastropod) , henoch schonlein purpura , perforin , dermatology , vasculitis , pathology , arthritis , bone marrow , immune system , cd8 , ecology , disease , biology
Hemophagocytic lymphohistiocytosis ( HLH ) is a fatal, hyper‐inflammatory syndrome that is characterized by untimely activation of macrophages, and manifests as cytopenia, organ dysfunction, and coagulopathy. Secondary HLH can be associated with infection, drugs, malignancy, and transplantation, and is mostly triggered by infection. Herein, we report the case of a patient with H enoch– S chönlein purpura ( HSP ) who developed severe HLH secondary to V aricella zoster infection.