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Primary orbital neuroblastoma in a 1‐month‐old boy
Author(s) -
Inazawa Natsuko,
Hatakeyama Naoki,
Hori Tsukasa,
Yamamoto Masaki,
Igarashi Keita,
Tadashi Hasegawa,
Ogino Jiro,
Tsutsumi Hiroyuki,
Suzuki Nobuhiro
Publication year - 2014
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/ped.12239
Subject(s) - medicine , neuroblastoma , enucleation , refractory (planetary science) , chemotherapy , radiation therapy , adrenal gland , surgery , pathology , genetics , physics , astrobiology , biology , cell culture
Neuroblastoma is a malignant tumor predominantly occurring in children and usually arising from the adrenal gland or sympathetic ganglia. We describe a neuroblastoma in a 1‐month‐old boy arising from his left orbital cavity. This tumor was refractory to chemotherapy or radiotherapy, requiring enucleation of the left eye for complete removal of the intraorbital tumor. Thereafter, he received high‐dose chemotherapy followed by autologous peripheral blood stem cell transplantation, and has been in complete remission for 3 years. Unlike neuroblastomas arising from the adrenal gland or sympathetic ganglia, primary orbital neuroblastoma may be refractory even in early infancy.