Neonatal pleural empyema caused by emm type 6 group A streptococcus

Since the mid‐1980s, there have been increasing reports of severe invasive group A streptococcal ( GAS ) disease in children and adults. There are few reports, however, of neonatal invasive disease, particularly neonatal pleural empyema caused by GAS . Although many mechanisms have been reported for the pathophysiology of invasive GAS infections, similar reports for neonates were unable to be located. Reported herein is the case of a 3‐day‐old girl with pleural empyema caused by GAS that demonstrated a high invasive capacity for human epithelial cells.