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Epidermolytic epidermal nevus caused by a somatic mutation in KRT2
Author(s) -
Mohamad Janan,
Samuelov Liat,
Assaf Sari,
Vodo Dan,
Sarig Ofer,
Sprecher Eli
Publication year - 2021
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.14529
Subject(s) - epidermolytic hyperkeratosis , dermatology , medicine , nevus , ichthyosis , dyskeratosis , mutation , somatic cell , genetics , biology , hyperkeratosis , cancer research , gene , melanoma
Superficial epidermolytic ichthyosis (formerly Ichthyosis bullosa of Siemens) is an uncommon condition caused by dominant mutations in KRT2 encoding keratin 2. Epidermolytic epidermal nevus due to somatic mutations in KRT2 is even rarer. Here, we report the third case of KRT2‐ associated epidermal nevus and review the literature.