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Darier sign in a teenager with primary cutaneous marginal zone lymphoma
Author(s) -
Leonard Nicholas,
Lal Karan,
Luffman Christina,
O'Donnell Patrick,
Jolley Lindsey,
Belazarian Leah
Publication year - 2020
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.14488
Subject(s) - medicine , marginal zone , rituximab , dermatology , lymphoma , sign (mathematics) , marginal zone b cell lymphoma , malt lymphoma , cutaneous lymphoma , pathology , b cell , immunology , mycosis fungoides , antibody , mathematical analysis , mathematics
Primary cutaneous marginal zone lymphoma (PCMZL) is a low‐grade B‐cell lymphoma that arises in the skin. An adolescent male presented with dermal nodules on the arms, legs, and back with a positive Darier sign, ultimately diagnosed as PCMZL. The nodules demonstrated a partial response to doxycycline in the setting of prior Lyme disease followed by a complete response to rituximab.

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