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Epidermal necrolysis as the presenting manifestation of pediatric lupus
Author(s) -
Bhattarai Dharmagat,
Vignesh Pandiarajan,
Chaudhary Himanshi,
Bharadwaj Niteesh,
Saini Lokesh,
Gupta Kirti,
Rawat Amit
Publication year - 2020
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.14324
Subject(s) - toxic epidermal necrolysis , medicine , dermatology , systemic lupus erythematosus , differential diagnosis , erythroderma , lupus erythematosus , pediatrics , pathology , immunology , disease , antibody
Stevens‐Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) represents the spectrum of skin lesions characterized by rashes, exfoliation, and sloughing usually following drug intake. Occasionally, TEN‐like cutaneous manifestations have also been described with systemic lupus erythematosus. Recognition of lupus in a child presenting with TEN‐like skin changes is clinically challenging and requires a high degree of suspicion. We describe the case of a child who had epidermal necrolysis as the presenting feature of lupus and had severe neurological complications. TEN‐like skin changes in association with severe neurological complications in pediatric lupus are uncommon. Lupus must be considered in the differential diagnosis of a child presenting with epidermal necrolysis with no provocative risk factors such as a history of exposure to medications.