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Melanoma arising in a patient with ataxia‐telangiectasia: A call for full skin examinations in this patient population
Author(s) -
Oska Sandra,
Zarbo Allison,
Yeager Danielle,
Friedman Ben J.,
Shwayder Tor
Publication year - 2020
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.14200
Subject(s) - medicine , ataxia telangiectasia , malignancy , dermatology , telangiectasia , incidence (geometry) , melanoma , population , ataxia , pediatrics , pathology , dna , genetics , physics , environmental health , dna damage , cancer research , optics , biology , psychiatry
Abstract Ataxia‐telangiectasia (A‐T) is an autosomal recessive, multisystem disorder characterized by cerebellar ataxia and oculocutaneous telangiectasias that present in early childhood. Increased incidence of malignancy is also associated with A‐T. Hematopoietic malignancies occur most commonly, with a majority being lymphoid cancers; however, there is a risk for other malignancies, such as breast, gastric, and other solid tumors. Herein, we report the case of a 28‐year‐old woman with A‐T with melanoma.