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Cutaneous manifestations of congenital malignant rhabdoid tumor: Unusual papillomatous plaques and other skin presentations
Author(s) -
Luu Minnelly,
Halbert Anne,
Yan Albert,
Rubin Adam,
McMahon Patrick,
Liang Marilyn,
Vadeboncoeur Sophie,
Frieden Ilona J.,
Maguiness Sheilagh
Publication year - 2020
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.14175
Subject(s) - medicine , presentation (obstetrics) , hamartoma , pathology , neurovascular bundle , differential diagnosis , dermatology , soft tissue , radiology
Background/Objectives Malignant rhabdoid tumors (MRT) are highly aggressive tumors with a predilection for the kidney, central nervous system, and soft tissues that usually affect young children under three years of age. Primary presentation in the skin is rarely reported, and features of the cutaneous manifestations are not well described. We report six cases of metastatic MRT that first manifested with congenital nodules and masses in the skin. Methods Retrospective case series. Results The cutaneous presentation of MRT may be heterogeneous and can present with solitary or multifocal skin lesions. Congenital polypoidal and papillomatous plaques, including those with histologic features of neurovascular hamartoma, appear to be a unique presentation of MRT in the infant. Conclusions Malignant rhabdoid tumor should be considered in the differential diagnosis of unusual skin tumors in neonates and infants.