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A case of self‐improving collodion ichthyosis in Vietnam
Author(s) -
Diep Quang Minh,
Luong Long Hoang,
Tran Thinh Huy,
Dinh Oanh Thi Lan,
Nguyen Hung Quoc,
Bui TheHung,
Ta Thanh Van,
Tran Van Khanh
Publication year - 2020
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.14128
Subject(s) - collodion , ichthyosis , congenital ichthyosis , medicine , lamellar ichthyosis , dermatology , phenotype , genetics , biology , membrane , gene
Autosomal recessive congenital ichthyosis is a heterogeneous group of congenital disorders characterized by aberrant skin cornification and diffuse skin scaling. Some patients with this condition are born encased in a collodion membrane which is later shed, revealing the underlying skin disorder. Self‐healing collodion baby (SHCB) is a less common phenotype of this disorder, accounting for about 10% of the patients, in which the membrane peels after several weeks, leaving no underlying skin aberration. Here, we report and discuss the diagnosis and management of an infant with SHCB in Vietnam due to compound heterozygous pathogenic mutations in TGM1 .