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Pemphigus‐like eruption as a complication of molluscum contagiosum treatment with imiquimod in a 5‐year‐old girl
Author(s) -
Zhong Connie S.,
Hasbun Maria Trinidad,
Jones Krystal M.,
Schmidt Birgitta A.R.,
Hussain Sadaf H.
Publication year - 2020
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.14115
Subject(s) - imiquimod , medicine , molluscum contagiosum , pemphigus , dermatology , complication , surgery
Pemphigus and pemphigus‐like reactions can be triggered by a variety of medications including topical therapies, such as imiquimod. While the association between imiquimod and pemphigus‐like reactions has been reported in adults, this is the first report of a generalized reaction beyond the site of imiquimod application in a child. The mechanism by which this occurs may be through a unique pathway, separate from the classic antibody‐mediated pathway. Our patient had a full recovery without recurrence after cessation of the inciting drug.