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Novel KIT mutation presenting as marked lentiginosis
Author(s) -
Tran Alain K.,
Pearce Annette,
LópezSánchez Marcos,
PérezJurado Luis A.,
Barnett Christopher
Publication year - 2019
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.13952
Subject(s) - medicine , hyperpigmentation , lentigo , dermatology , pathological , mutation , pigmentation disorder , girl , genetic counseling , genetics , pathology , gene , cancer research , biology , melanoma
Although lentigines are usually benign, they can be associated with a number of genetic syndromes in which neoplasms and other multi‐system pathological processes occur. Here, we report the case of a 6‐year‐old girl who presented with atypical lentiginosis and hyperpigmentation caused by a de novo genetic variant in the KIT gene.