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Microphthalmia and linear skin defects syndrome: Precise diagnosis guides prognosis
Author(s) -
Satcher Kerrie G.,
Maegawa Gustavo H. B.,
Schoch Jennifer J.
Publication year - 2019
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.13946
Subject(s) - microphthalmia , medicine , dermatology , skin lesion , biochemistry , chemistry , gene
Abstract Microphthalmia and linear skin defects syndrome ( MLS ) is a rare X‐linked dominant disorder characterized by microphthalmia and linear atrophic plaques of the face and neck. The diagnosis of MLS can be challenging secondary to both its rarity and to clinical overlap with Goltz syndrome. Whereas the skin lesions of MLS are more likely to improve in appearance with age, the lesions of Goltz are typically persistent.