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Response to ustekinumab in three pediatric patients with alopecia areata
Author(s) -
Aleisa Abdullah,
Lim Yeun,
Gordon Samantha,
Her Min Ji,
Zancanaro Pedro,
Abudu Minawaer,
Deverapalli Sandhya Chowdary,
Madani Abdulaziz,
Rosmarin David
Publication year - 2018
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.13699
Subject(s) - medicine , alopecia areata , ustekinumab , dermatology , disease , infliximab
Alopecia areata ( AA ) is relatively common and can have a significant impact on quality of life, especially in a pediatric population. Currently available treatments are often ineffective or have poor safety profiles. Recent studies have highlighted the importance of the Th1 pathway in the pathogenesis of AA , suggesting ustekinumab as a treatment modality for this disease. We present three pediatric AA patients who demonstrated hair regrowth after initiating ustekinumab.