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Diffuse cutaneous mastocytosis: Case report and literature review
Author(s) -
Hosking AnnaMarie,
Makdisi Joy,
Ortenzio Francesca,
Feraudy Sebastien,
Smith Janellen,
Linden Kenneth
Publication year - 2018
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.13651
Subject(s) - medicine , dermatology , cutaneous mastocytosis , skin biopsy , systemic mastocytosis , biopsy , pathology , disease
A 6‐month‐old boy was referred to our burn unit with a recurrent bullous dermatitis, fever, and emesis, originally diagnosed as staphylococcal scalded skin syndrome ( SSSS ) at an outside hospital. Infectious workup was negative and shave biopsy revealed a dense, diffuse dermal infiltrate of mast cells, consistent with diffuse cutaneous bullous mastocytosis—a rare variant of cutaneous mastocytosis. Treatment included a prolonged course of corticosteroids and antihistamines. Recognition of this rare form of mastocytosis is important, as it can be easily mistaken for other pediatric bullous diseases and is associated with life‐threatening complications including vasodilation, anaphylactic shock, gastrointestinal bleeding, and death.