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Superimposed linear atopic dermatitis
Author(s) -
LópezCedeño Angella,
NogueraMorel Lucero,
HernándezMartín Angela,
Happle Rudolf,
Torrelo Antonio
Publication year - 2018
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.13611
Subject(s) - atopic dermatitis , medicine , dermatology , loss of heterozygosity , disease , atopy , allergy , pathology , immunology , genetics , biology , allele , gene
Superimposed linear atopic dermatitis is rarely manifested in polygenic disease as a counterpart to type 2 segmental mosaicism of monogenic skin diseases. Linear arrangement following Blaschko lines represents more severe disease on a generalized background of atopic dermatitis, perhaps reflecting clonal loss of heterozygosity. Only three cases of superimposed linear atopic dermatitis have been reported; we describe three additional cases.