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Multiple Spitz nevi after allogeneic hematopoietic stem cell transplantation
Author(s) -
Song Yu Mee,
Kim Yoon Seob,
Seo HyunMin,
Bang Chul Hwan,
Lee Ji Hyun,
Park Young Min,
Lee Jun Young
Publication year - 2018
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.13566
Subject(s) - spitz nevus , medicine , hematopoietic stem cell transplantation , transplantation , lesion , pathology , umbilical cord , dermatology , trunk , chemoradiotherapy , nevus , surgery , radiation therapy , immunology , melanoma , ecology , cancer research , biology
Spitz nevus commonly appears as a solitary lesion. A 12‐year‐old male patient presented with a 6‐month history of several pigmented lesions on his trunk and lower extremities. He had undergone chemoradiotherapy and unrelated umbilical cord blood transplantation against recurring acute lymphoblastic leukemia for 6 years. After that, several pigmented lesions abruptly developed on his trunk and lower extremities, and the number of those increased significantly. Pathologically, the diagnosis of multiple Spitz nevi was made. In a clinical correlation, we diagnosed multiple Spitz nevi resulting from such an immunocompromised condition. This is the first description of clinical, dermoscopic, and histopathologic features of multiple Spitz nevi in the hematopoietic cell transplantation (HSCT) recipient child.