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Pernio as the presenting sign of blast crisis in acute lymphoblastic leukemia
Author(s) -
Park Kelly K.,
Tayebi Bailey,
Uihlein Lily,
Speiser Jodi,
Mir Adnan,
Gerami Pedram,
Mancini Anthony,
Kim Wendy
Publication year - 2017
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.13366
Subject(s) - medicine , lymphoblastic leukemia , nose , sign (mathematics) , dermatology , leukemia , pathology , immunology , surgery , mathematical analysis , mathematics
A previously healthy 5‐year‐old girl presented with acute onset of blue toes and red spots on the nose and fingers. The striking nature of these lesions, along with the finding of submandibular lymphadenopathy, prompted further evaluation. Laboratory findings were remarkable for anemia, high transaminase levels, and high blast count. Histopathologic findings were consistent with early pernio. Further examination revealed acute B‐cell lymphoblastic leukemia. Treatment of the leukemia led to resolution of the pernio.