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Mother Nature in Eczema: Maternal Factors Influencing Atopic Dermatitis
Author(s) -
Vaughn Alexandra R.,
Tannhauser Paige,
Sivamani Raja K.,
Shi Vivian Y.
Publication year - 2017
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.13149
Subject(s) - atopic dermatitis , medicine , offspring , etiology , disease , breastfeeding , skin barrier , immunology , dermatology , pregnancy , genetics , pediatrics , pathology , biology
Atopic dermatitis ( AD ) is a highly prevalent chronic inflammatory skin disease. Current knowledge about the etiology of AD suggests that it is multifactorial and involves the interaction of several factors, including environmental triggers, genetics, immunologic factors, and skin barrier dysfunction. The prenatal environment has a significant influence on fetal development, including the maturation of skin barrier function. This review summarizes maternal factors that have been reported to influence the development of AD in offspring, including maternal genetics, nutrition, breastfeeding, environment, and behaviors.