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Low‐Dose Cyclosporine A in the Treatment of Severe Atopic Dermatitis Complicated by Chronic Hepatitis C Virus Infection
Author(s) -
Gnarra Maria,
De Simone Clara,
Garcovich Matteo,
Garcovich Simone
Publication year - 2017
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.13115
Subject(s) - medicine , atopic dermatitis , refractory (planetary science) , chronic hepatitis , immunology , virus , hepatitis c virus , dermatology , hepatitis a virus , antiviral therapy , physics , astrobiology
Atopic dermatitis ( AD ) is the most frequent chronic inflammatory skin disorder in children and is usually accompanied by genetic and environmental factors. Effective management and treatment of AD is challenging and often requires systemic immunosuppressive therapy when refractory to topical treatments. We report a rare association between chronic hepatitis C virus ( HCV ) and severe AD , management of which required systemic cyclosporine because of its favorable effects on inflammatory and viral‐related clinical outcomes.