Premium
Pediatric Erythema Annulare Centrifugum Treated with Oral Fluconazole: A Retrospective Series
Author(s) -
Kruse Lacey L.,
KennerBell Brandi M.,
Mancini Anthony J.
Publication year - 2016
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.12909
Subject(s) - medicine , fluconazole , dermatology , occult , etiology , clearance , erythema , granuloma annulare , adverse effect , retrospective cohort study , surgery , antifungal , pathology , alternative medicine , urology
Abstract Objectives Erythema annulare centrifugum ( EAC ) is an uncommon eruption that may be a hypersensitivity reaction. Treatment of EAC is best accomplished by eliminating the underlying cause. Although many triggers have been reported, the inciting factor is unknown in most patients. We hypothesized that occult yeast overgrowth may trigger EAC in patients with EAC of unknown etiology. Methods Five children with EAC were treated empirically with oral fluconazole. These cases were retrospectively reviewed. Results Improvement was noted in all patients; three cleared entirely. Two patients experienced recurrences after successful treatment, which were treated with a second course of fluconazole. The treatment was well tolerated, without adverse effects. Conclusion Oral fluconazole was an effective treatment in five children with EAC.