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Agminated Fibroblastic Conective Tissue Nevus: A New Clinical Presentation
Author(s) -
Downey Camila,
Requena Luis,
Bagué Silvia,
Sánchez Martínez Miquel Ángel,
Lloreta Josep,
Baselga Eulalia
Publication year - 2016
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.12896
Subject(s) - dermatofibrosarcoma protuberans , elastin , dermis , connective tissue , medicine , pathology , differential diagnosis , reticular dermis , cd34 , nevus , dermatology , biology , melanoma , stem cell , cancer research , genetics
Connective tissue nevi are benign hamartomatous lesions in which one or several of the components of the dermis (collagen, elastin, glicosaminoglycans) show predominance or depletion. Recently, de Feraudy et al broadened the spectrum of connective tissue nevus, describing fibroblastic connective tissue nevus ( FCTN ), which is characterized by proliferation of CD 34 + cells of fibroblastic and myofibroblastic lineage. Only solitary papules and nodules have been described. We present the first case of FCTN with multiple agminated lesions on the leg of an infant and the difficulties encountered in the differential diagnosis with dermatofibrosarcoma protuberans.