Premium
Acquired Epidermodysplasia Verruciformis Associated with Human Papilloma Virus Type 14 in a Small Bowel Transplanted Child—A Case Report
Author(s) -
Hirschman Derek,
Tacastacas Joselin,
Rady Peter L.,
Tyring Stephen K.,
Cooper Kevin,
Honda Kord
Publication year - 2015
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.12734
Subject(s) - epidermodysplasia verruciformis , medicine , imiquimod , tacrolimus , cidofovir , transplantation , dermatology , malignant transformation , organ transplantation , virus , pathology , virology , surgery
A 3‐year‐old African American girl taking sirolimus and tacrolimus for a small bowel transplantation presented with hypopigmented macules and papules throughout her trunk. A biopsy diagnosed epidermodysplasia verruciformis ( EV ) that was found to be associated with human papillomavirus ( HPV ) type 14 according to polymerase chain reaction analysis. There are few cases of acquired EV in the setting of organ transplantation. Although there is no standardized treatment for acquired EV , prevention and surveillance for transformation to squamous cell carcinoma are primary concerns.