Premium
Intralesional Candida Antigen Immunotherapy for the Treatment of Recalcitrant and Multiple Warts in Children
Author(s) -
Muñoz Garza Fania Z.,
Roé Crespo Esther,
Torres Pradilla Mauricio,
Aguilera Peirò Paula,
Baltà Cruz Susana,
Hernández Ruiz María Eugenia,
Baselga Torres Eulàlia
Publication year - 2015
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.12667
Subject(s) - medicine , candida infections , immunotherapy , complete response , dermatology , surgery , antigen , adverse effect , chemotherapy , immunology , antifungal , cancer
Background Intralesional injection of Candida antigen appears to be an effective alternative for the treatment of warts. Aim To determine the efficacy and safety of this treatment. Methods We retrospectively reviewed records of all children who received intralesional injection of Candida antigen at our center from January 2008 to July 2013. Results From a total of 220 patients, 156 (70.9%) had a complete response, 37 (16.8%) had a partial response, and 27 (12.2%) had no improvement. An average of 2.73 treatments was needed. Forty‐seven of the patients with more than one wart (21.3%) also noted at least partial resolution of untreated warts at distant sites. Twenty‐seven of the 47 patients (57.4%) had complete resolution. All treated patients experienced some discomfort at the time of the injection, but no serious side effects were reported. Discussion We report our results using this approach in a large group of children. Conclusion Intralesional injection of Candida antigen is an effective and safe therapy for children with multiple and recalcitrant cutaneous warts.