Premium
Outpatient Home‐based Wet Wrap Dressings with Topical Steroids with Children with Severe Recalcitrant Atopic Dermatitis: A Feasibility Pilot Study
Author(s) -
Leloup Pauline,
Stalder JeanFrançois,
Barbarot Sébastien
Publication year - 2015
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.12602
Subject(s) - medicine , scorad , atopic dermatitis , refractory (planetary science) , dermatology , open label , surgery , randomized controlled trial , dermatology life quality index , physics , astrobiology , psoriasis
Abstract Wet wrapping ( WW ) appears to be effective in severe atopic dermatitis ( AD ) in children resistant to topical treatment. Seventeen children were included and were directed to use WW every night (≥6 hr) until lesions disappeared, followed by maintenance treatment of two to three treatments per week. The mean Scoring Atopic Dermatitis ( SCORAD ) score at baseline was 48.9. After 1 month of treatment the mean SCORAD score was 18.9, and efficacy was maintained after 3 months of treatment. The majority of patients were satisfied (91.7%) with the WW treatment; 92% considered it to be much more effective than the previous treatments received. WW was easy to perform for 75% of patients, 83% of patients stated that it was better tolerated, and 17% considered it to be tolerated equally to dermatologic corticosteroids without WW . The home WW program was continued on a maintenance basis for 75% of patients. This open‐label study showed that this program was a feasible and well‐tolerated alternative for the treatment of severe, refractory AD in children and adolescents.