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Successful Topical Rapamycin Treatment for Facial Angiofibromata in Two Children
Author(s) -
Pynn Emma V.,
Collins Jemma,
Hunasehally Prasad R. Y.,
Hughes Jenny
Publication year - 2015
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.12551
Subject(s) - medicine , sirolimus , tuberous sclerosis , dermatology , surgery , pathology
Topical sirolimus, or rapamycin, is known to inhibit tumorigenesis in tuberous sclerosis. We report two cases of successful treatment of children with facial angiofibromata and summarize the encouraging evidence of the effectiveness of this therapy in the literature.