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Cutaneous Epithelioid Hemangioendothelioma on the Sole of a Child
Author(s) -
CarranzaRomero Carmen,
MolinaRuiz Ana Maria,
Perna Monroy Cristian,
Cuevas Santos Jesús,
Requena Luis
Publication year - 2015
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.12539
Subject(s) - epithelioid hemangioendothelioma , medicine , hemangioendothelioma , pathology , soft tissue , vascular tumor , lymphatic system , immunohistochemistry
Epithelioid hemangioendothelioma ( EHE ) has been considered to be a low‐grade malignant vascular neoplasm, although follow‐up of recent series has demonstrated that EHE involving the skin and soft tissues should be better regarded as a fully malignant vascular tumor since it has more metastatic potential than previously thought. We report a case of an EHE involving the left sole of 6‐year‐old boy, the youngest patient with cutaneous EHE described to date. Immunohistochemical studies demonstrated a lymphatic endothelial line of differentiation for neoplastic cells. Cutaneous EHE is rare in childhood, with only five previously described cases.