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Unusually Large Patch‐Type Noninvoluting Congenital Hemangioma of the Shoulder: A Report of Two Cases
Author(s) -
Bonifazi Ernesto,
Cutrone Mario
Publication year - 2015
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.12510
Subject(s) - medicine , stain , histopathology , hemangioma , pathology , glut1 , staining , anatomy , glucose transporter , insulin
Noninvoluting congenital hemangiomas ( NICH s) are vascular tumors that are fully formed at birth and do not regress. Clinically, NICH s persist indefinitely over time. Histologically they are characterized by deep dermal lobules of small vessels with endothelial cells that do not stain with glucose transporter 1 ( GLUT 1). Two similar cases of unusually large, patch‐type NICH s of the shoulder in neonates were observed in the past 20 years in two pediatric dermatology units in Italy. In both cases, histopathology showed lobular collections of small vessels that did not stain with GLUT 1. The clinical features of the two cases remained unchanged over a follow‐up period of 10 and 4 years, respectively. The large size and flat appearance of the lesions could be due to their early onset during embryogenesis.