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Xanthoma Disseminatum Associated with Inflammatory Arthritis and Synovitis—A Rare Association
Author(s) -
Gupta Prashant,
Khandpur Sujay,
Vedi Kamal,
Singh Manoj K.,
Walia Ritika
Publication year - 2014
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.12388
Subject(s) - medicine , synovitis , pigmented villonodular synovitis , xanthoma , histiocytosis , dermatology , arthritis , pathology , rheumatoid arthritis , acromion , inflammatory arthritis , immunology , surgery , rotator cuff , disease
Xanthoma disseminatum ( XD ) is a rare, benign, non‐Langerhans cell histiocytosis characterized by disseminated xanthomatous lesions with a predilection for the face, flexures, and mucosae. Approximately 100 cases have been reported in the literature. We report XD in an 8‐year‐old boy with symmetric synovitis and arthritis involving the wrists and knees. This case is interesting in view of the association between arthritis and synovitis and XD , which to our knowledge has not been reported in the literature. This case has to be differentiated from multicentric histiocytosis, another non‐Langerhans cell histiocytosis, in which joint involvement is common.