Premium
Oral Glycopyrrolate for Refractory Pediatric and Adolescent Hyperhidrosis
Author(s) -
Kumar Monique G.,
Foreman Rebecca S.,
Berk David R.,
Bayliss Susan J.
Publication year - 2013
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.12236
Subject(s) - glycopyrrolate , medicine , hyperhidrosis , refractory (planetary science) , dermatology , pediatrics , oxybutynin , anesthesia , atropine , physics , astrobiology , alternative medicine , pathology , overactive bladder
Primary hyperhidrosis is a common disorder affecting children and adolescents, and it can have a significant negative psychosocial effect. Treatment for pediatric hyperhidrosis tends to be limited by low efficacy, low adherence, and poor tolerance. Oral glycopyrrolate is emerging as a potential second‐line treatment option, but experience with safety, efficacy, and dosing is especially limited in children. We present an institutional review of 12 children with severe, refractory hyperhidrosis treated with oral glycopyrrolate; 11 (92%) noted improvement and 9 (75%) would recommend oral glycopyrrolate to their friends. No significant side effects were noted. Our retrospective analysis suggests that oral glycopyrrolate is safe and effective in children with hyperhidrosis.