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Aplasia Cutis Congenita in a Setting of Fetus Papyraceus Associated with Small Fetal Abdominal Circumference and High Alpha‐Fetoprotein and Amniotic Acetylcholinesterase
Author(s) -
Mazza Joni M.,
Klein Janice F.,
Christopher Kurt,
Silverberg Nanette B.
Publication year - 2013
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.12228
Subject(s) - medicine , fetus , aplasia cutis congenita , obstetrics , aplasia , gestational age , umbilical cord , in utero , pregnancy , scalp , surgery , anatomy , genetics , biology
Fetus papyraceus is the fetal death of one or more fetuses in a multiparous pregnancy. The surviving infants can experience extensive aplasia cutis in an H‐shaped distribution over the flanks and abdomen as a consequence of the loss of their fetal sibling. We report the case of a monochorionic, diamniotic pregnancy complicated by a single fetal death at 13 weeks of gestational age. Aplasia cutis of the surviving twin was suggested in utero by three criteria: high amniotic and maternal alpha‐fetoprotein, detectable acetylcholinesterase, and small abdominal circumference on prenatal ultrasound. This constellation of findings in the setting of fetus papyraceus can be an indicator of aplasia cutis in the surviving fetus.