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Antibiotic Sensitivity and Resistance Patterns in Pediatric Staphylococcal Scalded Skin Syndrome
Author(s) -
Braunstein Inbal,
Wanat Karolyn A.,
Abuabara Katrina,
McGowan Karin L.,
Yan Albert C.,
Treat James R.
Publication year - 2013
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.12195
Subject(s) - staphylococcal scalded skin syndrome , clindamycin , medicine , empiric therapy , antibiotics , penicillin , empiric treatment , dermatology , staphylococcus aureus , pediatrics , microbiology and biotechnology , bacteria , biology , genetics
Historical resistance patterns often guide empiric antibiotic choices in staphylococcal scalded skin syndrome ( SSSS ), but little is known about the difference in susceptibility between SSSS and other childhood staphylococcal infections. A retrospective chart review of culture‐confirmed cases of SSSS seen in the inpatient dermatology consultation service at the Children's Hospital of Philadelphia between 2005 and 2011 was performed. Most cases of SSSS at our institution are due to oxacillin‐susceptible S taphylococcus aureus , and approximately half of the cases are due to clindamycin‐resistant strains. Clindamycin and a penicillinase‐resistant penicillin are suggested as empiric treatment for SSSS until culture susceptibility data are available to guide therapy.